Snail + Slug (pSer246) Antikörper (HRP)

Produktnummer ABIN1412240

Der Kaninchen Polyklonal Anti--Antikörper wurde für ELISA validiert. Er ist geeignet, in Proben von Human zu detektieren.

Kurzübersicht für Snail + Slug (pSer246) Antikörper (HRP) (ABIN1412240)

Target: Snail + Slug

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: HRP

Applikation: ELISA

Produktdetails

Bindungsspezifität: pSer246

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human SNAIL around the phosphorylation site of Ser246

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Gentamicin sulfate

Vorsichtsmaßnahmen: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Snail + Slug

Hintergrund:

Synonyms: SNAIL + SLUG phospho S246 + S251, SNAIL + SLUG phospho Ser246 + Ser251, SNAILSer246 + SLUGSer251, dJ710H13.1, MGC10182, Neural crest transcription factor Slug, Protein sna, Protein snail homolog 1, Protein snail homolog 2, Protein snail homolog, Slug homolog zinc finger protein, Slug zinc finger protein, SLUGH, SLUGH 1, SLUGH1, SLUGH2, SNA, Sna protein, SNAH, SNAI 2, snai1, SNAI1_HUMAN, Snai2, SNAI2_HUMAN, Snail 2, Snail homolog 1 Drosophila, Snail homolog 2, Snail2, WS 2D, WS2D, Zinc finger protein SLUG, Zinc finger protein SNAI1, Zinc finger protein SNAI2.

Background: This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin. SLUG is involved in epithelial-mesenchymal transitions (EMT) involving E-cadherin repression which is known to play an important role in tumor progression amd neural tube formation. SLUG also has antiapoptotic activity. Mutations in this gene may be associated with sporadic cases of neural tube defects (referenced from Entrez gene).

Gen-ID: 6311

UniProt: O95863